I can think of:
- King Kong (1930's)
- King Kong (1970's)
- Ghostbusters (the giant Stay-Puff man)
- Ghostbusters II (Statue of Liberty)
- The Creature from 20,000 Fathoms
- Godzilla (1999)
Chris F. chimed in last night with:
- Q
Any other films with really-big things in New York?